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KMID : 0360220070480101354
Journal of the Korean Ophthalmological Society
2007 Volume.48 No. 10 p.1354 ~ p.1361
Serous Retinal Detachment in Patients with Choroidal Neovascularization Following Photodynamic Therapy
Kim Cin-Oo

Chung Hum
Heo Jang-Won
Abstract
Purpose: To quantify the development and resolution of serous retinal detachment in patients with choroidal neovascularization (CNV) following photodynamic therapy (PDT).

Methods: Six eyes of five patients who developed serous retinal detachment two days after PDT were included in this study. Retinal thickness was measured by optical coherence tomography (OCT) before PDT, and at two days, seven days, and three weeks after PDT. The number of PDT and the greatest linear dimension (GLD) of the CNV lesion were recorded.

Results: Serous retinal detachment was demonstrated on OCT at two days after PDT. Retinal elevation increased significantly from 313.2 ¥ìm before PDT to 640.7 ¥ìm two days after PDT (P<0.01); elevation and decreased to 303.2 ¥ìm seven days after PDT, and decreased to 223.4 ¥ìm three weeks after PDT. The mean number of PDT treatments 2.0 (range: 1~3), and the mean GLD before PDT was 3122.8¡¾1275.9 ¥ìm.

Conclusions: This study suggest that serous retinal detachment in patients with CNV may develop following PDT but may also resolve spontaneously seven days after PDT.
KEYWORD
Choroidal neovascularization, Photodynamic therapy, Serous retinal detachment
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